Gentavet 10% oral solution

Form of application: oral administration.

Active ingredient: gentamicin sulfate.

Packaging: 1000-mL flasks.

Gentavet 10 % for oral administration contains 100 mg of gentamycin sulfate.  The spectrum of action of gentamycin is similar to that of other aminoglycosides but this antibiotic is more active with respect to Staphylococcus aureus, Escherichia coli, Pseudomonas auruginosa.

Gentamycin in the form of oral solution was released for such purposes as follows:

1. Gentamycin inhibits protein synthesis in bacterial cells;
2. Drug resistance develops very rarely and slowly;
3. It is used to treat diseases of the gastrointestinal tract only for it is not absorbed from the gastrointestinal tract, acts locally, produces no toxic effect in the organism of an animal; and
4. Unlike powder, 10% solution does not block a system to water poultry.

 Diluted in water, the preparation is stable for 24 hours.

 At the poultry farms where Gentavet 10 % oral solution was used, following the determination of isolated microflora sensitivity to this preparation, specialists in veterinary ensured themselves of easiness to use and quality of this preparation.  Taking account of preparation pricing policy, as well as the method of administration and dosage, economical efficiency of Gentavet 10 % preparation is several times as much higher than that of other preparations containing other antibiotics and chemotherapeutical agents provided that sensitivity to such other preparations is also high.

In quality, Gentavet 10 % equals analogs while in easiness to use it ranks over existing drugs.

Characters

A clear colorless solution.

Composition

1 mL of Gentavet 10 % contains:

• 100 mg of gentamycin sulfate.

Pharmalogical action

The active ingredient of the preparation - gentamycin sulfate – is an antibiotic of the aminoglycoside group active with respect to gram-positive and gram-negative microorganisms. The mechanism of action of the preparation is blocking protein synthesis in a bacterial cell.  Drug resistance arises rarely and develops slowly.

Uses

For the treatment and prevention of diseases of the gastrointestinal tract, respiratory tracts, urogenital system, skin and other bacterial etiology diseases.

Dosage and administration

Gentavet 10 % for oral administration in the following doses:

1. Calves: First day - 5cm³ /100 kg of body weight orally (divide in two doses), then 4cm³ per 100 kg of body weight once daily. Treatment duration is between 3 days and 5 days.
2. Pigs: 5 cm³ per 100 kg of body weight daily (divide in two doses of water or 5 cm³ per 10 L of water).

To treat dysentery: 11 cm3 to 22 cm³/100 L of water to drink. Treatment duration is between 3 days and 5 days, once daily.
-     Poultry: 20 cm³/100 L of water to drink or 1000 cm³/5000 L water. Treatment duration is between 5 days and 7 days

Contraindications

Hypersensitivity to gentamycin.  Do not administer to animals with an affected kidney function; do not administer at the same time with other aminoglycoside antibiotics and those of a nephrotoxic action.

Precautions

Animals may only be slaughtered for meat in 45 days of the last intramuscular injection of the preparation; milk is fit for human food in 3 days.  If slaughtered during this period of time, feed meat and milk to non-productive animals or dispose them.
If administrated orally, meat is fit for food in 10 days to 14 days.

How supplied

Solution for oral administration in 1000-mL vials.

Storage

Store protected from light in a dry place at a room temperature (List B).  Shelf life is 2 years from the date of manufacture.